Evolution & origins of complexity

Scientists Discover Ancient Single-Celled Ancestors Still Live On in Your Blood

Your immune system is older than animals. By a lot.

Scientists Discover Ancient Single-Celled Ancestors Still Live On in Your Blood
Visual brief for “Scientists Discover Ancient Single-Celled Ancestors Still Live On in Your Blood”.

What happened

Kyoto University researchers rebuilt the evolutionary family tree of blood cells and found that key immune cells trace back to single-celled ancestors from about 700 million years ago. Macrophages, the cells that engulf invaders, most closely resembled those ancient microbes, and a gene called FOS links the lineage all the way back.

What I love about this is the picture of complexity it paints. Modern blood did not appear from nowhere. Early animals reused genetic toolkits inherited from single-celled life, then branched mast cells, T cells, red blood cells, and B cells off that foundation over hundreds of millions of years.

Complexity tends to be remixed, not invented. The same method may help trace the deep origins of diseases like cancer. A good reminder that we are walking archives of an extremely long experiment.

Source

Reported by Scientists Discover Ancient Single-Celled Ancestors Still Live On in Your Blood via sciencedaily.com, published May 27, 2026.